Liquisolid Systems to Improve the Dissolution of Furosemide
نویسندگان
چکیده
منابع مشابه
Liquisolid Systems to Improve the Dissolution of Furosemide
A liquisolid system has the ability to improve the dissolution properties of poorly water soluble drugs. Liquisolid compacts are flowing and compactable powdered forms of liquid medications. The aim of this study was to enhance the in vitro dissolution properties of the practically water insoluble loop diuretic furosemide, by utilising liquisolid technique. Several liquisolid tablets were prepa...
متن کاملFormulation Development and Evaluation of Liquisolid Systems to Improve the Dissolution Rate of Ketoprofen
Liquisolid compacts were used to formulate water insoluble drugs in non-volatile solvents and converting into acceptably flowing and compressible powders. The main objective of present investigation was to enhance the dissolution rate of water insoluble drug ketoprofen by using liquisolid technique. Several liquisolid tablets were prepared by using different carrier materials such as microcryst...
متن کاملImproving the dissolution properties of spironolactone using liquisolid technique
In this study the effect of liquisolid technique on the dissolution profile of spironolactone was evaluated. Different formulations of spironolactone liquisolid compacts were prepared using various amounts of non-volatile vehicles (Poly ethylene glycol 400 and glycerin). The ratio of microcrystalline cellulose (as carrier) to silica (as coating powder material) was 20 for all formulations. Afte...
متن کاملEnhancement of Dissolution Rate of Indomethacin Using Liquisolid Compacts
The potential of liquisolid systems to improve the dissolution properties of a water-insoluble agent (indomethacin) was the purpose of this survey. In this study, different formulations of liquisolid tablets using different co-solvents (non-volatile solvents) were prepared and the effect of several amounts of them on the dissolution behaviour of indomethacin was investigated. It is worth mentio...
متن کاملEnhancement of Dissolution Properties of Amlodipine Besylate Using Liquisolid Technique
The most promising method for enhancing solubility, therefore promoting the rate of dissolution is the formation of liquisolid compacts.[2]With Liquisolid technique as described by Spireas liquid formulations such as solutions or suspensions of poorly soluble drugs in a non-volatile liquid vehicle are converted into acceptably flowing and compressible powders, by simple physical blending with s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientia Pharmaceutica
سال: 2010
ISSN: 0036-8709
DOI: 10.3797/scipharm.0912-23